Type of Study: Clinical Trial

Sponsor / Support: LACOG

Primary Objectives: To evaluate laryngectomy-free survival of a treatment regimen consisting of induction chemo-immunotherapy, followed by radioimmunotherapy, followed by consolidation immunotherapy.

Design: This a prospective, single-arm, multi-institutional, open label, phase 2 trial evaluating the effects of induction chemo-immunotherapy, followed by radioimmunotherapy, followed by consolidation immunotherapy in patients with locally advanced squamous cell carcinoma of the larynx who are candidates for organ preservation.

Sample Size: 39 patients

Principal Investigator: William William

Countries LATAM: Brazil

Clinicaltrials.gov Identifier: NCT04943445