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LACOG 0419 – NEOSAMBA

  /    /  LACOG 0419 – NEOSAMBA

Evaluation of Sequencing of Anthracyclines and Taxanes for Locally Advanced HER2-negative Breast Cancer

Type of Study: Clinical Trial

Sponsor / Support: LACOG / GBECAM

Primary Objectives: To evaluate in a phase III randomized clinical trial the comparison between an anthracycline-initiated neoadjuvant chemotherapy regimen (AC-T) versus a taxane-initiated regimen (T-AC) in patients with locally advanced HER2- breast cancer

Design: Phase III, open-label, multicenter randomized clinical trial

Sample Size: 494 patients

Principal Investigator: José Bines

Countries LATAM: Brazil

Clinicaltrials.gov Identifier: NCT04540692

The study is open to patients participation in the following research sites:

INCA - Instituto Nacional de Câncer / Rio de Janeiro / RJ / Brazil

Hospital de Clínicas de Porto Alegre / Porto Alegre / RS / Brazil

CEPON - Centro de Pesquisas Oncológicas / Florianópolis / SC / Brazil

Hospital do Câncer de Barretos / Barretos / SP / Brazil

UNICAMP - Universidade Estadual de Campinas / Campinas / SP / Brazil

São Camilo Oncologia / São Paulo / SP / Brazil

Hospital Araújo Jorge / Goiânia / GO / Brazil

Hospital Jardim Amália / Volta Redonda / RJ / Brazil