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LACOG 1018 – PALBO in Ovarian Cancer

  /    /  LACOG 1018 – PALBO in Ovarian Cancer

Palbociclib plus letrozole combination after progression to second line chemotherapy for women with ER/PR-positive ovarian cancer

Type of Study: Clinical Trial

Sponsor / Support: LACOG

Primary Objectives: To evaluate the efficacy, assessed by 12 weeks progression-free survival (PFS), of Palbociclib plus Letrozole in ER/PR positive serous ovarian cancer that progressed on second line chemotherapy.

Design: Multicenter, single arm, phase II clinical trial.

Sample Size: 39 patients

Principal Investigator: Fernanda Bronzon Damian

Countries LATAM: Brazil

Clinicaltrials.gov Identifier: NCT03936270 

The study is open to patients participation in the following research sites:

BP - A Beneficência Portuguesa de São Paulo / São Paulo / SP / Brazil

UFMG - Universidade Federal de Minas Gerais / Belo Horizonte / MG / Brazil

INCA - Instituto Nacional de Câncer / Rio de Janeiro / RJ / Brazil

CPO-RS - Centro de Pesquisa em Oncologia / Porto Alegre / RS / Brazil

ICESP - Instituto do Câncer do Estado de São Paulo / São Paulo / SP / Brazil

Ongoing studies

Breast
GBECAM 0115 – AMAZONA III
LACOG 0115 – LORELEI
LACOG 0221 – BRAVE
LACOG 0413 – Male Breast Cancer
LACOG 0419 – NEOSAMBA
LACOG 0615 – LATINABreast
LACOG 0715 – PALLAS
LACOG 2118 – ALEXANDRA/IMpassion 030

Gastrointestinal
LACOG 0119
LACOG 0222 – GASPAR
LACOG 0421 – ACTION HIV
LACOG/GTG 1318 – Anal Registry

Genitourinary
LACOG 0121 – PET-PSMA
LACOG 0217 – IRONMAN
LACOG 0218 – Hercules
LACOG 0519 – PEACE III
LACOG 0620 – ExBAT
LACOG 1120 – RENAL REGISTRY
LACOG 1818 – Prostate Cancer Registry
LACOG 2018 – Foundation Penile

Gynecological
LACOG 0223 / GOG-3073 – ROSELLA
LACOG 0521 – MADONNA
LACOG 0820 – EVITA LATAM
LACOG 0920 – Senticol III
LACOG 1018 – PALBO in Ovarian Cancer
LACOG 1220 – CONOR

Head and Neck
LACOG 0319
LACOG 0720 – SMART-KEY

Lung
LACOG 0116 – LATINO LUNG
LACOG 0118 – RELANCE
LACOG 0120 – EAP durva lung cancer
LACOG 0322 – EDUR-BRA
LACOG 0821
LACOG 1918
LACOG 2218 – PACIFIC BRAZIL

Radiation
LACOG 0122 – RADIANT

Closed studies

Breast
LACOG 0111 – MGH
LACOG 0312 – METASTATIC BC
LACOG 0414
LACOG 0801 – GLICO

Genitourinary
LACOG 0415 – APA in Prostate Cancer
LACOG 0515 – Testicular Registry
LACOG 1518 – Bladder Cancer Registry

Gynecological
LACOG 0215 – EVITA

Head and Neck
LACOG 0318 – Induction

Lung
LACOG 0211 – ALK
LACOG 0417 – CNS MTX
LACOG 0618
Parsimony

Neuro
LACOG 0619

Other studies
LACOG 0213 – AUGMENT
LACOG 0214 – FINEP